2-Nitro-1H-benzimidazole is an organic compound characterized by its fused bicyclic structure, which consists of a benzene ring and an imidazole ring. The presence of a nitro group (-NO2) at the second position of the benzimidazole framework contributes to its chemical reactivity and properties. This compound typically appears as a yellow to orange solid and is sparingly soluble in water but more soluble in organic solvents such as ethanol and acetone. It exhibits notable biological activity, making it of interest in pharmaceutical research, particularly for its potential antimicrobial and antifungal properties. The compound's molecular structure allows for various chemical modifications, which can enhance its biological efficacy or alter its physical properties. Additionally, 2-nitro-1H-benzimidazole can participate in various chemical reactions, including nucleophilic substitutions and reductions, making it a versatile intermediate in organic synthesis. Safety precautions should be observed when handling this compound, as nitro compounds can be hazardous and may pose environmental risks.

2-Nitro-1H-benzimidazole

5709-67-1: 1H-Benzimidazole, 2-nitro-, 2-Nitro-1H-1,3-benzodiazole, 2-Nitro-1H-benzimidazole, 2-Nitro-1H-benzo[d]imidazole, 2-Nitrobenzimidazole, 5-Pyrimidinecarboxylic Acid, 4-(4-Chlorophenyl)-1,2,3,4-Tetrahydro-1,6-Dimethyl-2-Oxo-, 2-(Ethylthio)Ethyl Ester, Benzimidazole, 2-nitro-, NSC 107509

2-Nitro-1H-benzo[d]imidazole is an analog of benzimidazole compounds. It is used in the preparation of antibodies. 2-Nitro-1H-benzo[d]imidazole reacts with hydrochloric acid to form a trifluoroacetic acid, which can be purified by trichloroacetic acid and recrystallized from methanol. The purity of the product can be checked using a UV spectrophotometer, and it has a melting point of 141°C.

2-Nitro-1H-benzo[d]imidazole is also used as a substrate for polymerase chain reactions (PCR). PCR is an analytical technique that uses DNA polymerase to generate many copies of a region of DNA from one or more samples. In this process, 2-Nitro-1H-benzo[d]imidazole

CAS 5709-67-1: 2-Nitro-1H-benzimidazole

2-Nitro-1H-benzo[d]imidazole

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2-Nitro-1H-benzo[d]imidazole

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2-Nitro-1H-benzo[d]imidazole

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1H-Benzimidazole,2-nitro-(9CI)

Ref: IN-DA00EWKO