CAS 57096-02-3: 5,7-dihydroxy-2-(4-hydroxyphenyl)-8-methoxy-4H-chromen-4-one

4'-Hydroxywogonin is a bioactive flavonoid, which is derived primarily from the roots of the plant *Scutellaria baicalensis*. This compound is a naturally occurring flavone, a subclass of flavonoids, known for its potential therapeutic properties. The mode of action of 4'-Hydroxywogonin involves its ability to modulate various cellular signaling pathways. It is particularly noted for its anti-inflammatory and antioxidant effects, which are mediated through the inhibition of pro-inflammatory cytokines and the scavenging of free radicals, respectively. The applications of 4'-Hydroxywogonin are being explored in a variety of biomedical research fields. It has shown promise in preclinical studies related to the treatment of inflammatory disorders, neurodegenerative diseases, and certain types of cancer. Researchers are particularly interested in its potential to modulate immune responses and protect against oxidative stress-related cell damage. Further studies are necessary to fully elucidate its mechanisms and efficacy in clinical settings, but its natural origin and bioactivity make it a compound of significant interest in pharmacological research.

4'-Hydroxywogonin, anti-inflammatory ,reduce TNF-α, IL-6, and IL-1β, inhibited the TAK1/IKK/NF-κB , and reduced the phosphorylation of MAPKs and the PI3/Akt.