CAS 5786-21-0: Clozapine
Formula:C18H19ClN4
InChI:InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
InChI key:InChIKey=QZUDBNBUXVUHMW-UHFFFAOYSA-N
SMILES:CN1CCN(C=2C=3C(NC=4C(N2)=CC(Cl)=CC4)=CC=CC3)CC1
Synonyms:- 5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-
- 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
- 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
- Apo-Clozapine
- Asaleptin
- Azaleptin
- Azaleptine
- Brn 0764984
- Ccris 9171
- Clorazil
- Cloril
- See more synonyms
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Clozapine for peak identification CRS
CAS:Clozapine for peak identification CRSFormula:C18H19ClN4Molecular weight:326.8233Clozapine
CAS:Controlled ProductApplications An antipsychotic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)Formula:C18H19ClN4Color and Shape:Off-WhiteMolecular weight:326.82Clozapine
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFormula:C18H19ClN4Color and Shape:Yellow PowderMolecular weight:326.12982Clozapine, 97%
CAS:Potent, selective muscarinic antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C18H19Cl4Purity:97%Molecular weight:326.83Clozapine Resolution Mixture
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureColor and Shape:Yellow Crystalline PowderMolecular weight:203.09061Clozapine - Bio-X ™
CAS:Controlled ProductClozapine, a dibenzodiazepine, demonstrates antagonistic activity at the dopamine receptors, further binding to serotonin (5-HT1A, 5-HT2A-C, 5-HT6, 5-HT7), alpha 1 and 2 adrenergic, histamine 1 and M1-M5 muscarinic receptors. In particular, its partial 5-HT1A agonist behaviour, its low affinity for the D2 Dopamine receptors and its antagonistic activity at 5-HT2A receptors, are properties, which make it useful as an antipsychotic drug. The FDA has approved Clozapine for use in the alleviation of symptoms in treatment-resistant schizophrenia patients, such as the risk of self-harm. Although not yet approved by the FDA, Clozapione exerts positive effects in Parkinson’s disease and bipolar disorder treatments. However, Clozapione is not currently a first line-therapy option, as it may cause agranulocytosis and other side effects such as orthostatic hypotension and hypersalivation. Clozapine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C18H19ClN4Purity:Min. 95%Color and Shape:Yellow PowderMolecular weight:326.82 g/mol5-Acetyl-8-chloro-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one
CAS:Formula:C15H11ClN2O2Color and Shape:NeatMolecular weight:286.713Clozapine
CAS:ClozapineFormula:C18H19ClN4Purity:99.9%Color and Shape:Off-WhiteMolecular weight:326.12982Clozapine
CAS:Formula:C18H19ClN4Purity:>98.0%(GC)(T)Color and Shape:Light yellow to Amber to Dark green powder to crystalMolecular weight:326.83
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