CAS 58-05-9: Leucovorin
Formula:C20H23N7O7
InChI:InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1
InChI key:InChIKey=VVIAGPKUTFNRDU-ABLWVSNPSA-N
SMILES:C(=O)N1C2=C(NCC1CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)NC(N)=NC2=O
Synonyms:- (6R,S)-5-Formyltetrahydrofolate
- 10-Formyl-7,8-dihydrofolic acid
- 5-Formyl-5,6,7,8-tetrahydrofolic acid
- 5-Formyltetrahydrofolic Acid
- 5-Formyltetrahydrofolsaure
- 5-Formyltetrahydropteroylglutamic acid
- <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
- <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
- Acide 5-Formyltetrahydrofolique
- Acido 5-Formiltetrahidrofolico
- CF
- See more synonyms
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Folinic Acid
CAS:Applications Folinic Acid is used in combination with 5-fluorouracil in the treatment of colorectal cancers. It also functions as a useful antidotal therapy medication for decreasing the toxic effect of methotrexate overdosing. References He, J., et al.: Cancer Sci., 111, 253 (2020); Labriet, A., et al.: Pharmacogenomics, 20, 1179 (2019); Pannu, A. K.: Curr. Drug Metab., 20, 714 (2019)Formula:C20H23N7O7Color and Shape:NeatMolecular weight:473.45Calcium Folinate
CAS:Formula:C20H21CaN7O7Purity:>98.0%(T)(HPLC)Color and Shape:Light orange to Yellow to Green powder to crystalineMolecular weight:511.51Folinic acid
CAS:Folinic acid is a vitamin-B9 that is used as a cofactor for enzymes involved in the synthesis of DNA and RNA. It is also used to diagnose various infectious diseases, with high values found in patients with cancer or autoimmune diseases. Folinic acid has been shown to have dose-dependent effects on mammalian cells, exhibiting toxicities at higher concentrations. Folinic acid can be used to repair damaged DNA by acting as a glycosidase that breaks down the glycosidic bond between the base and sugar.Formula:C20H23N7O7Purity:(%) Min. 97%Color and Shape:White PowderMolecular weight:473.44 g/mol(2S)-2-[[4-[(2-Amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
CAS:Formula:C20H23N7O7Purity:98%Color and Shape:SolidMolecular weight:473.4393Folinic acid
CAS:Folinic acid (Leucovorin) is a biofolic acid that can be used in the treatment of methotrexate, often in combination with Methotrexate (MTX) to reduce MTX-Formula:C20H23N7O7Purity:99.7%Color and Shape:Crystals From Water With 3 Mol Of Water Of Crystallization SolidMolecular weight:473.44
![(2S)-2-[[4-[(2-Amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pent…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003A0Z.jpg&w=3840&q=75)
