
CAS 58-54-8: Ethacrynic acid
Formula:C13H12Cl2O4
InChI:InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)
InChI key:InChIKey=AVOLMBLBETYQHX-UHFFFAOYSA-N
SMILES:C(C(CC)=C)(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1
Synonyms:- (2,3-Dichloro-4-(2-Methylene-1-Oxobutyl)Phenoxy)-Acetic Acid
- (4-(2-Methylenebutyryl)-2,3-Dichlorophenoxy)Acetic Acid
- 2,3-Dichloro-4-(2-Methylenebutyryl)Phenoxyacetic Acid
- 2,3-Dichloro-4-(2-ethyl-1-oxo-2-propenyl)-phenoxyacetic acid
- 2-[2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic acid
- 2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
- 4-(2-Methylenebutyryl)Phenoxyacetic Acid
- Acetic acid, 2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-
- Acetic acid, [2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-
- Acetic acid, [2,3-dichloro-4-(2-methylenebutyryl)phenoxy]-
- Acide Etacrynique
- See more synonyms
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Found 15 products.
ETACRYNIC ACID CRS
CAS:ETACRYNIC ACID CRSFormula:C13H12Cl2O4Color and Shape:PowderMolecular weight:303.138Etacrynic acid for system suitability CRS
CAS:Etacrynic acid for system suitability CRSFormula:C13H12Cl2O4Color and Shape:PowderMolecular weight:303.138Ethacrynic Acid
CAS:Controlled ProductApplications Ethacrynic Acid is a diuretic used to treat high blood pressure and swelling caused by congestive heart failure, liver failure and kidney failure. References Beyer, et al.: J. Pharmacol. Exp. Ther., 147, 1 (1965); Kim., et al.: Am. J. Cardiol., 27, 407 (1971); Williamson, H.E., et al.: J. Clin. Pharmacol., 17, 663 (1977);Formula:C13H12Cl2O4Color and Shape:Off-WhiteMolecular weight:303.14Ethacrynic Acid
CAS:Formula:C13H12Cl2O4Color and Shape:White To Off-White SolidMolecular weight:303.14Ethacrynic acid
CAS:Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂,也是NF-κB 信号传导途径的有效抑制剂,并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道,从而导致气道平滑肌细胞松弛。它是利尿剂,具有抗炎特性,可减轻类维生素 A 诱导的小鼠耳部水肿。Formula:C13H12Cl2O4Purity:100% - 99.15%Color and Shape:Crystals Physical Description White Solid (Ntp 1992)Molecular weight:303.14Ethacrynic acid
CAS:Ethacrynic acid is used to inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C13H12Cl2O4Molecular weight:303.14Ethacrynic acid
CAS:Controlled ProductEthacrynic acid is a non-competitive, reversible inhibitor of the Na+/K+-ATPase. It has been shown to be effective against cancer tissues and infectious diseases such as malaria, tuberculosis, and leishmaniasis. Ethacrynic acid inhibits 2,4-dichlorobenzoic acid (2,4-DCBA)-induced tumor growth in mice by inducing apoptosis in human leukemia cells. Ethacrynic acid also inhibits mitochondrial membrane potential and cellular physiology by decreasing the activity of enzymes which are involved in energy metabolism.Formula:C13H12Cl2O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:303.14 g/molEtacrynic acid
CAS:Etacrynic acidFormula:C13H12Cl2O4Purity:99.2%Color and Shape:Off-WhiteMolecular weight:302.01126Ethacrynic Acid
CAS:Carboxylic acids with additional oxygen function and thFormula:C13H12Cl2O4Color and Shape:White Off-White PowderMolecular weight:303.14