CAS 583-78-8: 2,5-Dichlorophenol

2,5-Dichlorophenol

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2,5-Dichlorophenol is a chlorinated phenol that has been used as an industrial chemical for many years. It has been shown in animal and human studies to cause kidney damage, especially in women. Chronic exposure to 2,5-dichlorophenol can lead to chronic kidney disease. The mechanism of this toxicity is not well understood but may be due to its ability to react with diazonium salt and form reactive intermediates that are more toxic than the starting material. 2,5-Dichlorophenol also reacts with acylating agents such as triclosan in the body and forms a mixture of isomeric products. This reaction occurs at high pH levels, which may be present in the human bladder or urine samples. The glucuronide conjugate of 2,5-dichlorophenol is excreted in the urine and can be measured using laser ablation techniques or by gas chromatography-mass spectrometry

Applications 2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Wang, F., et al.: Bull. Enviro. Contamin. Toxicol., 89, 316 (2012); Zhong, W., et al.: J. Hazard. Mat., 217, 286 (2012);