CAS 58880-19-6: Trichostatin A
Formula:C17H22N2O3
InChI:InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
InChI key:InChIKey=RTKIYFITIVXBLE-QEQCGCAPSA-N
SMILES:C([C@@H](/C=C(/C=C/C(NO)=O)\C)C)(=O)C1=CC=C(N(C)C)C=C1
Synonyms:- (2E,4E)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
- (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
- (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
- (R)-(+)-Trichostatin A
- 2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-
- 2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
- 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, [R-(E,E)]-
- 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
- 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
- TSA
- Trichostatin A
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Found 8 products.
Trichostatin A
CAS:Trichostatin A (TSA) is a natural derivative of diene isohydroxamic acids.Formula:C17H22N2O3Purity:96.01% - 98.3%Color and Shape:Off-White PowderMolecular weight:302.37Trichostatin A
CAS:Formula:C17H22N2O3Purity:≥ 95.5%Color and Shape:White to off-white or light-yellow powderMolecular weight:302.372,4-Heptadienamide,7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
CAS:Formula:C17H22N2O3Purity:98%Color and Shape:SolidMolecular weight:302.3682Trichostatin A from Streptomyces sp.
CAS:Trichostatin A from Streptomyces sp.Formula:C17H22N2O3Purity:By hplc: 99.21% (Typical Value in Batch COA)Color and Shape: off-white powderMolecular weight:302.37g/molTrichostatin A
CAS:A potent inhibitor of histone deacetylases (HDACs) of class I and II with anti-tumoral activity. The compound blocks HDAC catalytic activity by chelating zinc ion in the enzyme’s active site. Extensively used in research as epigenetic modifier able to block cell growth and downregulate proliferation-associated factors. It has also been reported that trichostatin A induces apoptosis via a histone-modification independent mechanism in oral squamous cell carcinoma cell lines. Initially discovered as anti-fungal compound from Streptomyces hygroscopicus for the control of fungal infections caused by the genus Trichophyton.Formula:C17H22N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:302.37 g/molTrichostatin A
CAS:Formula:C17H22N2O3Purity:>98.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:302.37Trichostatin A
CAS:Controlled ProductApplications Trichostatin A is a known inhibitor of fibrosis in vitro and in vivo, and is used as an anticancer agent. Potent differentiation inducer of friend leukemic cells. References Mori, K. et al.: Tetra., 44, 6013 (1988); Meng, F. et al.: Brit. J. Canc., 108, 579 (2013); Yang, L. et al.: Mol. Pharm., 83, 671 (2013);Formula:C17H22N2O3Color and Shape:Off-WhiteMolecular weight:302.37
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