CAS 5911-08-0: (Chloromethyl)cyclopropane

Applications (Chloromethyl)cyclopropane is a used as a reagent to synthesize 6-alkylamino-9-alkylpurines, compounds that have potential to be antipsychotic agents. (Chloromethyl)cyclopropane is also used as a reagent to prepare acylmorphinans, a class of compounds that have analgesic effects in rats. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Kelley, J., et al.: J. Med. Chem., 40, 3207 (1997); Mohacsi, E., et al.: J. Med. Chem., 28, 1177 (1985)

(Chloromethyl)cyclopropane

Chloromethylcyclopropane is a toxic chemical that is used in the synthesis of pharmaceutical preparations. It is a reagent that can be used to produce carbon-carbon bonds by reacting with diethyl succinate, which creates the formation of chloromethylcyclopropane. The reaction solution can be purified using a solvent such as dichloromethane or chloroform and then reacted with chlorine atom, hydrogen chloride, and chloride to produce the desired products. Chloromethylcyclopropane reacts with nucleophilic attack to form an activated intermediate that leads to the addition of another molecule. This reaction releases nicotinic acetylcholine (NA) which is an important neurotransmitter in the central nervous system, and carbonyl group. Halides are able to react with chloromethylcyclopropane due to its electron-attracting properties. Activation energies are required for this reaction since it involves a stepwise process where one molecule must break

(Chloromethyl)cyclopropane was used in the synthesis of (lithiomethyl)cyclopropane and homoallyllithium via 4,4?-di-tert-butylbiphenyl or naphthalene-catalysed lithiation reaction. On reaction with isolable dialkylsilylene affords 5-silaspiro[4.4]nonane derivative. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.