CAS: 591230-99-8

Transcrocetinate disodium is a potential anticancer agent that has been shown to inhibit the activity of polymerase chain reaction (PCR) in vitro. It also inhibits DNA synthesis and mitochondrial function, leading to neuronal death. Transcrocetinate disodium may be used as an experimental model for radiation-induced myocardial infarcts in rats. This drug also has a number of physiological effects, including inhibition of platelet aggregation and vasoconstriction. It is not known whether transcrocetinate disodium alters crocin levels or crocetin production in vivo.

Transcrocetinate disodium (Disodium trans-crocetinate), extracted from saffron (Crocus sativus L.), is a high-affinity antagonist of NMDA receptor.

Trans Sodium Crocetinate(TSC), also known as Disodium trans-crocetinate or Sodium crocetinate, is potentially for the treatment of glioblastoma. Trans Sodium Crocetinate improves amyloid-β degradation in monocytes from Alzheimer's Disease patients. trans-crocetin inhibit glutamatergic synaptic transmission in rat cortical brain slices. Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases.

Transcrocetinate disodium