CAS 5939-37-7: 7-Hydroxymethotrexate
Formula:C20H22N8O6
InChI:InChI=1S/C20H22N8O6/c1-28(8-12-18(32)26-16-14(23-12)15(21)25-20(22)27-16)10-4-2-9(3-5-10)17(31)24-11(19(33)34)6-7-13(29)30/h2-5,11H,6-8H2,1H3,(H,24,31)(H,29,30)(H,33,34)(H5,21,22,25,26,27,32)/t11-/m0/s1
InChI key:InChIKey=HODZDDDNGRLGSI-NSHDSACASA-N
SMILES:NC1=C2C(NC(=O)C(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=NC(N)=N1
Synonyms:- 7-Hydroxymethotrexate
- <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
- <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
- Glutamic acid, N-[p-[[(2,4-diamino-7-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-
- Glutamic acid, N-[p-[[(2,4-diamino-7-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-
- N-[(4-{[(2,4-diamino-7-oxo-7,8-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]-L-glutamic acid
- N-[(4-{[(2,4-diamino-7-oxo-7,8-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]glutamic acid
- N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
- NSC 380962
- N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
- L-Glutamic acid, N-[4-[[(2,4-diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
- See more synonyms
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Found 8 products.
7-Hydroxy Methotrexate Ammonium
CAS:Controlled ProductApplications 7-Hydroxy Methotrexate Ammonium Salt is a metabolite of Methotrexate (M260675), which is used as an antineoplastic and antirheumatic. References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),Formula:C20H22N8O6·NH3Color and Shape:Yellow To BrownMolecular weight:487.477-Hydroxymethotrexate
CAS:7-Hydroxymethotrexate, major Methotrexate metabolite, inhibits dihydrofolate reductase and DNA synthesis by blocking folic acid conversion.Formula:C20H22N8O6Purity:95%Color and Shape:SolidMolecular weight:470.447-Hydroxy methotrexate
CAS:Methotrexate is a chemotherapy drug that can be given intravenously or orally. It is used to treat certain cancers, such as leukemia, and various other diseases, such as arthritis and psoriasis. Methotrexate inhibits the synthesis of DNA by blocking enzymes involved in the process of DNA replication. This drug also has been shown to inhibit the production of energy in cells by inhibiting mitochondrial enzymes. Methotrexate may also have a beneficial effect on disease activity, but this effect has not been confirmed in clinical trials. The stability of methotrexate in human serum depends on its pH and concentration.Formula:C20H22N8O6Purity:Min. 95%Color and Shape:Yellow SolidMolecular weight:470.44 g/mol7-Hydroxy Methotrexate Trisodium Salt
CAS:Formula:C20H19N8O6·3NaColor and Shape:Yellow SolidMolecular weight:467.42 3*22.997-Hydroxy Methotrexate-d3 Ammonium Salt
CAS:Controlled ProductApplications 7-Hydroxy Methotrexate-d3 is a deuterated metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic.Formula:C20H22D3N9O6Color and Shape:NeatMolecular weight:490.49
