CAS: 59587-01-8

2-Chloro-4-[(dimethylcarbamoyl)amino]benzoic acid is an anticancer agent that inhibits the growth of cancer cells by inhibiting the enzyme catalysis that is required for the synthesis of DNA. This drug is a synthetic compound with an active methylene group and an ester hydrochloride group. 2-Chloro-4-[(dimethylcarbamoyl)amino]benzoic acid also has a hydroxy group, which can be activated by enzymes such as enamine to form a reactive methylene, which reacts with other molecules to form reaction products. The mechanism of 2-chloro-4-[(dimethylcarbamoyl)amino]benzoic acid is similar to that of other anticancer drugs such as amine and amide.

Applications 2-Chloro-4-[(dimethylcarbamoyl)amino]benzoic Acid is a chlortoluron metabolite that was studied in transgenic tobacco plants. References Shiota, N., et al.: Pestic. Biochem. Physiol., 54, 190 (1996)