D-Glutamic acid, N-(4-aminobenzoyl)-, with the CAS number 5959-18-2, is an amino acid derivative characterized by the presence of both a glutamic acid moiety and a 4-aminobenzoyl group. This compound features a carboxylic acid functional group, which is typical of amino acids, and an amine group attached to the benzene ring, contributing to its potential as a ligand in biochemical applications. The presence of the aromatic ring enhances its stability and may influence its solubility and reactivity in various solvents. D-Glutamic acid is known for its role in protein synthesis and metabolism, while the 4-aminobenzoyl group can impart unique properties, such as increased binding affinity to specific receptors or enzymes. This compound may be utilized in research settings, particularly in studies involving neurotransmission or as a building block in the synthesis of more complex molecules. Its specific characteristics, such as melting point, solubility, and reactivity, would depend on the conditions under which it is studied.

D-Glutamic acid, N-(4-aminobenzoyl)-

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Folinic Acid Impurity 5 (4-Aminobenzoyl D-Glutamic Acid)

Applications N-(4-Aminobenzoyl)-D-glutamic acid is an intermediate in the synthesis of R-Methotrexate which is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),


CAS 5959-18-2: D-Glutamic acid, N-(4-aminobenzoyl)-

Folinic Acid Impurity 5 (4-Aminobenzoyl D-Glutamic Acid)

Ref: 4Z-F-068014

N-(4-Aminobenzoyl)-D-glutamic Acid

Ref: TR-A593820