CAS 60-81-1: Phloridzin
Formula:C21H24O10
InChI:InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1
InChI key:InChIKey=IOUVKUPGCMBWBT-QNDFHXLGSA-N
SMILES:C(CCC1=CC=C(O)C=C1)(=O)C2=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C=C(O)C=C2O
Synonyms:- 1-Propanone, 1-[2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-
- 1-[2-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
- 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
- 2'-(β-D-Glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenon
- 2'-(β-D-glucopiranosiloxi)-4',6'-dihidroxi-3-(4-hidroxifenil)propiofenona
- 2'-(β-D-glucopyrannosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone
- 2'-(β-D-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone
- Dihydrochalcone 2′-β-<span class="text-smallcaps">D</span>-glucopyranoside
- Floridzin
- Nsc 2833
- Phloretin 2'-O-glucoside
- See more synonyms
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Found 11 products.
Phloridzin
CAS:Controlled ProductApplications It is a dihydrochalcone occurring in all parts of the apple tree except the mature fruit. Once thought to occur in pear, plum, cherry trees and other Rosaceae. Inhibitor of Na+-glucose cotransporters (SGLT). inhibits both SGLT1 and SGLT2 with low therapeutic selectivity. Cytotoxic to Breast Cancer cells with potent antioxidant and antibacterial activity. Produces renal glycosuria and blocks intestinal glucose absorption. Normalizes insulin sensitivity in diabetic rats. References Moelwyn-Hughes EA, 1930. J Gen Physiol. Jul 20;13(6):807-17.Chang-Ik, 2016. Molecules, 21, 1136Fernando W, et al. 2016. Carcinogenesis. 2016 Oct;37(10):1004-13Formula:C21H24O10Color and Shape:NeatMolecular weight:436.41Phlorizin
CAS:Formula:C21H24O10Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:436.41Phloridzin
CAS:Phloridzin is a flavonoid glycoside, which is primarily sourced from apple trees and other members of the Rosaceae family. It is naturally found in the bark, roots, and other parts of the plant. The mode of action of phloridzin involves its function as an inhibitor of the sodium-glucose transporters (SGLT1 and SGLT2). By blocking these transporters, phloridzin prevents the reabsorption of glucose in the renal tubules, thus promoting the excretion of glucose through urine. Phloridzin is predominantly used in scientific research focusing on diabetes and glucose metabolism. It serves as a tool to study glucose transport mechanisms and has been instrumental in the development of SGLT2 inhibitors, a class of antidiabetic drugs. Additionally, its antioxidant properties make phloridzin of interest in studies related to oxidative stress and its impact on cellular functions. Beyond these applications, phloridzin is also explored for its potential benefits in obesity research and botanical studies centered on its role and function within the Rosaceae family.Formula:C21H24O10Purity:Min. 95%Color and Shape:White PowderMolecular weight:436.41 g/molPhloridzin
CAS:Phloridzin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C21H24O10Purity:(HPLC) ≥99%Color and Shape:PowderMolecular weight:436.42Phlorizin
CAS:Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .Formula:C21H24O10Purity:99.58% - 99.76%Color and Shape:Solid CrystallineMolecular weight:436.41Phloridzin
CAS:Formula:C21H24O10Purity:≥ 98.0%Color and Shape:Off-white to light yellow powderMolecular weight:436.41Phloridzin
CAS:Natural glycosideFormula:C21H24O10Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:436.42
