CAS: 6019-39-2

OAC2

OAC2, an Oct4 activator, boosts iPSC creation from embryonic fibroblasts, similar to OAC1.

N-(1H-Indol-5-yl)benzamide is a tetraaryl compound that acts as a catalyst. It has been shown to be active against Gram-positive bacteria, such as Streptococcus pneumoniae and Staphylococcus aureus, at 10 μM. This compound has high activity against these bacteria and is more stable at higher temperatures. N-(1H-Indol-5-yl)benzamide has also been shown to have good stability in the presence of clarithromycin, which is an antibiotic used to treat bacterial infections. This drug can form a complex with clavulanic acid (a β-lactamase inhibitor) and thus can inhibit bacterial growth by binding to the ribosomal RNA of the bacteria. The molecular weight of N-(1H-indol-5-yl)benzamide is 169 g/mol and its functional groups are hydroxyl, carbonyl, and car

Applications N-(1H-Indol-5-yl)benzamide is a octamer-binding transcription factor 4 activating compound that activated Oct4 and Nanog promoters, which are essential regulators of embryonic stem cell (ESC) pluripotency and key to the reprogramming process. References Li, W.D., et al.: Proceed. Nation. Acad. Sci. U.S.A., et al.: 109, 20853 (2012);