CAS 6040-19-3: Cucurbitacin A
Formula:C32H46O9
InChI:InChI=1S/C32H46O9/c1-17(34)41-27(2,3)12-11-23(37)31(8,40)25-21(36)14-29(6)22-10-9-18-19(13-20(35)26(39)28(18,4)5)32(22,16-33)24(38)15-30(25,29)7/h9,11-12,19-22,25,33,35-36,40H,10,13-16H2,1-8H3/b12-11+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
InChI key:InChIKey=IHTCCHVMPGDDSL-IVNGUWCNSA-N
SMILES:C(O)[C@]12[C@]([C@@]3(C)[C@](C)(CC1=O)[C@@]([C@@](C(/C=C/C(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C3)[H])(CC=C4[C@]2(C[C@H](O)C(=O)C4(C)C)[H])[H]
Synonyms:- (2β,9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-19-norlanosta-5,23-diene-3,11,22-trione
- 19-Nor-9β,10α-lanosta-5,23-diene-3,11,22-trione, 2β,16α,20,25-tetrahydroxy-9-(hydroxymethyl)-, 25-acetate, (E)-
- 19-Norlanosta-5,23-diene-3,11,22-trione, 2,16,20,25-tetrahydroxy-9-(hydroxymethyl)-, 25-acetate
- 19-Norlanosta-5,23-diene-3,11,22-trione, 25-(acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-, (2.beta.,9.beta.,10.alpha.,16.alpha.,23E)-
- 19-Norlanosta-5,23-diene-3,11,22-trione, 25-(acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-, (2β,9β,10α,16α,23E)-
- Cucurbitacin A
- Cucurbitacine A
- NSC 94743
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Found 5 products.
Cucurbitacin A
CAS:Cucurbitacin A inhibits cancer growth in A-549 NSCLC cells by inducing apoptosis, targeting m-TOR/PI3K/Akt signalling pathway and G2/M cell cycle.Formula:C32H46O9Purity:95%~99%Color and Shape:PowderMolecular weight:574.711Cucurbitacin A
CAS:Controlled ProductCucurbitacin A is a polyphenolic secondary metabolite that has been shown to have a variety of biological activities. It has been shown to inhibit HIV-1 replication and induce apoptosis in cancer cells. Cucurbitacin A also inhibits the growth of human prostate cancer cells by inhibiting the expression of proteins involved in cell proliferation, such as cyclin D1 and p27. Cucurbitacin A also has potent anticancer activity against a broad range of cancer cells including breast, lung, colon, leukemia, melanoma, and ovarian cancers. Moreover, cucurbitacin A shows promise for the treatment of heart disease because it has been shown to inhibit platelet aggregation. The chemical stability and chemical composition make cucurbitacin A an attractive candidate for use as a pharmaceutical preparation.Formula:C32H46O9Purity:Min. 95%Molecular weight:574.71 g/molCucurbitacin A
CAS:Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/Formula:C32H46O9Purity:98%Color and Shape:SolidMolecular weight:574.7
