5-Aminopyridine-3-carboxamide, with the CAS number 60524-14-3, is an organic compound characterized by its pyridine ring structure, which is substituted with an amino group and a carboxamide group. This compound typically appears as a solid and is soluble in polar solvents due to the presence of the carboxamide functional group, which can engage in hydrogen bonding. The amino group contributes to its basicity, allowing it to participate in various chemical reactions, including nucleophilic substitutions. 5-Aminopyridine-3-carboxamide is of interest in medicinal chemistry and may exhibit biological activity, potentially serving as a precursor or intermediate in the synthesis of pharmaceuticals. Its structural features suggest that it could interact with biological targets, making it a candidate for further research in drug development. Additionally, the compound's stability and reactivity can be influenced by environmental factors such as pH and temperature, which are important considerations in both laboratory and industrial applications.

5-aminopyridine-3-carboxamide

60524-14-3: 5-Amino-3-pyridinecarboxamide, 3-Pyridinecarboxamide, 5-Amino-, 5-Aminonicotinamide

5-Amino-3-pyridinecarboxamide is an analog of nicotinamide that has been shown to have tumor-modulating activity. It has been shown to inhibit the growth of tumor cells in a maximally tolerated dose and inhibits hypoxic tumor growth. 5-Amino-3-pyridinecarboxamide is also structurally related to 6-methylmercaptopurine, which has been shown to induce tumor regression, but without the toxic side effects of 6-methylmercaptopurine. Studies have shown that 5-amino-3 pyridinecarboxamide inhibits the proliferation of breast cancer cells by inhibiting riboside synthesis, which may be due to its structural similarity to adriamycin, an antitumor antibiotic.

CAS 60524-14-3: 5-aminopyridine-3-carboxamide

5-Amino-3-pyridinecarboxamide

Ref: 3D-FA143707

5-Amino-3-pyridinecarboxamide

Ref: 10-F076704

5-Amino-3-Pyridinecarboxamide

Ref: 54-OR1011808

5-Amino-3-pyridinecarboxamide

Ref: IN-DA003MEF