6-Chloro-2-methyl-1H-indole is an organic compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of a chlorine atom at the 6-position and a methyl group at the 2-position contributes to its unique chemical properties. This compound is typically a solid at room temperature and is known for its potential applications in pharmaceuticals and agrochemicals due to its biological activity. It may exhibit various reactivity patterns typical of indole derivatives, including electrophilic substitution and nucleophilic reactions. The chlorine substituent can influence the compound's electronic properties, potentially enhancing its reactivity or altering its interaction with biological targets. Additionally, 6-chloro-2-methyl-1H-indole may be soluble in organic solvents, making it suitable for various synthetic applications. Safety data should be consulted for handling and storage, as halogenated compounds can pose health risks. Overall, this compound represents a valuable structure in medicinal chemistry and materials science.

6-chloro-2-methyl-1H-indole

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6-Chloro-2-methylindole is a neurotoxic compound that belongs to the indole class. It is an analog of serotonin, which is found in plants and animals. 6-Chloro-2-methylindole has been shown to cause neurotoxic effects in rats by altering 5-hydroxytryptamine (5-HT) levels in the brainstem and cerebral cortex. This compound also has a toxic effect on the brainstem when injected intraperitoneally or into the cerebral ventricles of experimental animals. 6CMI was also observed to have significant neurotoxic effects in the brains of rats after it was injected intraperitoneally or into the cerebral ventricles.

6CMI inhibits 5HT synthesis through oxidative deamination and thus leads to depletion of this neurotransmitter from nerve terminals and consequent central nervous system depression. In addition, 6CMI may act as a false neurotransmitter at postsynaptic receptors in some cases, thereby

CAS 6127-17-9: 6-chloro-2-methyl-1H-indole

6-Chloro-2-methylindole

Ref: 3D-FC142134

6-Chloro-2-methyl-1H-indole

Ref: 54-OR7950

6-Chloro-2-methylindole

Ref: 10-F034041