2-(4-Bromophenyl)-1H-indole, with the CAS number 6127-49-7, is an organic compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of a bromophenyl group at the 2-position of the indole ring introduces significant electronic and steric effects, influencing its reactivity and interactions. This compound typically exhibits a solid state at room temperature and is sparingly soluble in water but more soluble in organic solvents such as ethanol and dichloromethane. It may display interesting biological activities, making it a subject of interest in medicinal chemistry and drug development. The bromine substituent can enhance the compound's lipophilicity and may also participate in electrophilic substitution reactions. Additionally, 2-(4-bromophenyl)-1H-indole can serve as a building block in the synthesis of more complex molecules, contributing to its utility in various chemical applications. Safety data should be consulted for handling, as halogenated compounds can pose environmental and health risks.

2-(4-bromophenyl)-1H-indole

6127-49-7: 1H-indole, 2-(4-bromophenyl)-,  2-(4-Bromophenyl)-1H-indole

2-(4-BROMO-PHENYL)-1H-INDOLE

2-(4-Bromophenyl)-1H-indole

2-(4-Bromophenyl)-1H-indole is a ligand, which binds to the benzodiazepine receptor in the central nervous system. 2-(4-Bromophenyl)-1H-indole is synthesised and tested for its affinity for this receptor. The uptake of 2-(4-bromophenyl)-1H-indole into rat brain tissue is studied using autoradiography. It is found that 2-(4-bromophenyl)-1H-indole has high affinity for the benzodiazepine binding site on rat brain membranes and modulates the activity of GABA receptors, which causes sedation. The effects of halogens on 2-(4-bromophenyl)-1H-indole are investigated by measuring their effect on its uptake into rat brain tissue. Flumazenil, an antagonist of benzodiazepine receptors, blocks the effects of 2-(4-bromophenyl)-1H

CAS 6127-49-7: 2-(4-bromophenyl)-1H-indole

2-(4-BROMO-PHENYL)-1H-INDOLE

Ref: IN-DA00E9T9

2-(4-Bromophenyl)-1H-indole

Ref: 10-F229612

2-(4-Bromophenyl)-1H-indole

Ref: 3D-GAA12749

2-(4-Bromophenyl)-1H-Indole

Ref: 54-OR1009753