CAS 613-03-6: 1,2,4-Triacetoxybenzene

1,2,4-Triacetoxybenzene is a chemical that belongs to the group of halogenated aromatic compounds. It is used as a precursor for the production of pharmaceuticals and agrochemicals. The compound can be synthesized by reacting 1,2-dichlorobenzene with acetic acid, followed by hydrolysis with hydrochloric acid. When heated in the presence of hydrogen chloride, 1,2-dichlorobenzene reacts with acetic acid to form 1,2-dichloroethane and acetyl chloride. 1,2,4-Triacetoxybenzene is an antiplatelet agent that has been shown to inhibit platelet aggregation in vitro. This effect may be due to its ability to inhibit the synthesis of quinones and nitric oxide (NO). In addition to inhibiting platelet aggregation, it also inhibits both DNA and RNA synthesis in bacteria when irradiated with ultraviolet light

1,2,4-Triacetoxybenzene

Applications 1,2,4-Triacetoxybenzene, can be used in preparation of two marine aminated hydroxynaphthazarins, echinamines A and B. References Pokhilo N. D., et al.: Journal of natural products, 69(8), undefined (2006-8-29);