CAS 619-08-9: Nitrofungin

2-Chloro-4-nitrophenol

2-Chloro-4-nitrophenol: phenolic COX inhibitor, reduces prostaglandins, lessens inflammation and pain.

2-Chloro-4-nitrophenol, is frequently used as building blocks for dyes, plastics, explosives. It acts as a catalytic agent, petrochemical additive and used in organic synthesis. It can react with sulfuric acid dimethyl ester to produce 2-chloro-4-nitro-anisole. This reaction will need reagents K2CO3 and xylene. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Chloro-4-nitrophenol

2-Chloro-4-nitrophenol (2CP) is a chemical that has been found to be an optical sensor for nitrite ion. It reacts with nitrite ion at a pH of 5 and changes its color from yellow or orange to red. 2CP is also an antimicrobial agent and has shown biological properties against bacteria, including the ability to inhibit bacterial growth and reduce the number of bacteria in human serum. The optimum concentration for the inhibition of bacterial growth was found to be 0.5 mg/mL, which is much lower than the concentration used in other studies. The genus, bacterial strain, and pH were all found to influence the activity of 2CP against bacteria. Process optimization trials have shown that 4-hydroxycinnamic acid can be used as an alternative substrate for 2CP's reaction with nitrite ion. Monoclonal antibodies were also developed that are specific for transfer reactions with nitrate ion and can be used as a detection system for nit

Applications 2-Chloro-4-nitrophenol is used as a sole source of carbon and nitrogen by Cupriavidus strain a3. References Tiwari, J., et al.: Bioresour. Technol., 223, 184-191 (2017)