
CAS 61926-22-5: Ethidium homodimer
Formula:C46H48N8·2ClH·2Cl
InChI:InChI=1S/C46H46N8.4ClH/c47-33-13-17-37-39-19-15-35(49)29-43(39)53(45(41(37)27-33)31-9-3-1-4-10-31)25-7-21-51-23-24-52-22-8-26-54-44-30-36(50)16-20-40(44)38-18-14-34(48)28-42(38)46(54)32-11-5-2-6-12-32;;;;/h1-6,9-20,27-30,49-52H,7-8,21-26,47-48H2;4*1H
InChI key:InChIKey=ZKAJUKABUUJRLB-UHFFFAOYSA-N
SMILES:C(CCNCCNCCC[N+]=1C(=C2C(=C3C1C=C(N)C=C3)C=CC(N)=C2)C4=CC=CC=C4)[N+]=5C(=C6C(=C7C5C=C(N)C=C7)C=CC(N)=C6)C8=CC=CC=C8.[Cl-].Cl
Synonyms:- 5,5'-(1,2-Ethanediylbis(imino-3,1-propanediyl))bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
- 5,5'-(4,7-Diazadecamethylene)-bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
- 5,5'-(Ethylenebis(iminotrimethylene))bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride
- EthD 1
- Ethidium homodimer 1
- Phenanthridinium, 5,5'-(1,2-ethanediylbis(imino-3,1-propanediyl)bis(3,8-diamino-6-phenyl-, dichloride, dihydrochloride
- Phenanthridinium, 5,5′-[1,2-ethanediylbis(imino-3,1-propanediyl)]bis[3,8-diamino-6-phenyl-, chloride, hydrochloride (1:2:2)
- Phenanthridinium, 8-Amino-3-Ammonio-5-[3-[[2-[[3-(3,8-Diamino-6-Methyl-5-Phenanthridiniumyl)Propyl]Amino]Ethyl]Amino]Propyl]-6-Phenyl-, Chloride, Hydrochloride (1:2:2)
- Ethidium homodimer
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Found 5 products.
Ethidium homodimer I solution
CAS:Controlled ProductFormula:C46H48N8•2Cl•2HClColor and Shape:NeatMolecular weight:712.93+2(35.45)+2(36.46)Ethidium homodimer
CAS:Ethidium homodimer is an anti-cancer compound that inhibits the synthesis of DNA and RNA. This compound has shown significant cytotoxicity against cultured cells, which may be due to its ability to inhibit energy metabolism in the mitochondria and disrupt cell nuclei. Ethidium homodimer also inhibits polymerase chain reaction (PCR) by binding to inhibitor molecules and prevents replication of human DNA. It has been shown to induce apoptosis in HL60 cells, a type of white blood cell that is used as a model for leukemia. Ethidium homodimer has also been shown to inhibit cancerous growths in animal models and can be used for the treatment of bowel disease.Formula:C46H48N8·2Cl·2HClPurity:Min. 95%Molecular weight:856.78 g/molEthD-1
CAS:EthD-1 is a cell-impermeant viability indicator. It acts as a high-affinity nucleic acid stain.Formula:C46H49Cl2N8Color and Shape:SolidMolecular weight:784.85