CAS 6199-67-3: (+)-Cucurbitacin B
Formula:C32H46O8
InChI:InChI=1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
InChI key:InChIKey=IXQKXEUSCPEQRD-DKRGWESNSA-N
SMILES:C[C@]12[C@@](C)([C@@]([C@@](C(/C=C/C(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C1)[H])CC(=O)[C@]3(C)[C@]2(CC=C4[C@]3(C[C@H](O)C(=O)C4(C)C)[H])[H]
Synonyms:- (23E)-2,16,20-trihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
- (2S,4R,9beta,16alpha)-2,16,20-trihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
- (2S,4R,9beta,16alpha,17xi,23E)-2,16,20-trihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
- (2S,4R,9beta,16alpha,23E)-2,16,20-trihydroxy-9,10,14-trimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
- (2β,9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione
- 19-Nor-9β,10α-lanosta-5,23-diene-3,11,22-trione, 2β,16α,20,25-tetrahydroxy-9-methyl-, 25-acetate
- 19-Norlanosta-5,23-diene-3,11,22-trione, 25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-, (2β,9β,10α,16α,23E)-
- Amarine
- Cucurbitacine B
- Hy-N 0416
- NSC 144154
- See more synonyms
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Found 10 products.
Cucurbitacin B
CAS:Cucurbitacin B analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C32H46O8Purity:(HPLC) ≥95%Color and Shape:PowderMolecular weight:558.72Cucurbitacin B
CAS:Controlled ProductCucurbitacin B is a triterpenoid compound, which is derived from plants primarily within the Cucurbitaceae family. This compound exhibits its mode of action through the inhibition of the JAK-STAT signaling pathway, effectively disrupting processes that are critical for cell survival and proliferation. As a result, Cucurbitacin B is being extensively studied for its antiproliferative and pro-apoptotic properties, especially in the context of cancer research. The uses and applications of Cucurbitacin B are largely rooted in its potential as a therapeutic agent. Its ability to interfere with key cellular pathways has made it a topic of significant interest in exploring anticancer strategies. Furthermore, due to its anti-inflammatory properties, it is also being investigated for use in treating inflammatory disorders. Studies have suggested that Cucurbitacin B could serve a dual role in managing malignancies and inflammation, making it a valuable subject in biomedical research. Its natural origin and potent activity define its significance within the scientific community, where ongoing research continues to unravel its full potential.Formula:C32H46O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:558.7 g/molCucurbitacin B
CAS:Cucurbitacin B (cucB) is a triterpenoid constituent of Cucurbitaceae vegetables and a promising phytochemical for cancer prevention, cucB induces G(2) arrest and apoptosis through a STAT3-independent but ROS-dependent mechanism in SW480 cells.Formula:C32H46O8Purity:95%~99%Color and Shape:White powderMolecular weight:558.712Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purity:97.10% - 99.33%Color and Shape:SolidMolecular weight:558.7Cucurbitacin B
CAS:Controlled ProductApplications Cucurbitacin B is a tetracyclic triterpenoid, which can induce apoptosis in human hepatoma cells. It can also induce DNA damage and autophagy in MCF-7 breast cancer cells.In the wild, watermelons, cucumbers, and muskmelons produce bitter Cucurbitacins to defend against preditors. Humans have bred these fruits to eliminate these compounds thereby yielding fruits that are more appealing to our palate. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Sun, Y., et al.: Eur. J. Pharmacol. 768, 28 (2015); Ren, G., et al.: J. Nat. Med. 69, 522 (2015); C&E News p. 10, Dec. 5, 2016jFormula:C32H46O8Color and Shape:NeatMolecular weight:558.70Cucurbitacin B
CAS:Formula:C32H46O8Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:558.71Cucurbitacin B
CAS:Formula:C32H46O8Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:558.71Cucurbitacin b
CAS:Carboxylic acid with additional oxygen functionsFormula:C32H46O8Purity:≥ 90.0 % (HPLC)Color and Shape:PowderMolecular weight:558.71
