N-(4-Methylphenyl)urea, also known as p-tolylurea, is an organic compound characterized by the presence of a urea functional group attached to a para-methylphenyl group. Its molecular structure consists of a urea moiety (NH2CONH2) linked to a p-tolyl group (C6H4(CH3)-). This compound typically appears as a white crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. N-(4-Methylphenyl)urea is primarily used in research and industrial applications, including as a reagent in organic synthesis and as a potential herbicide. It exhibits moderate toxicity, necessitating careful handling and appropriate safety measures during use. The compound's properties, such as melting point and boiling point, can vary based on purity and environmental conditions. Overall, N-(4-Methylphenyl)urea is an important compound in the field of organic chemistry, contributing to various chemical processes and applications.

N-(4-Methylphenyl)urea

622-51-5: 1-(4-Methylphenyl)Urea, 1-p-Tolylurea, 4-Methylphenylurea, 4-Tolylurea, N-(4-Methylphenyl)urea, N-p-Tolylurea, NSC 66557, Urea, (4-methylphenyl)-, Urea, N-(4-methylphenyl)-, Urea, p-tolyl-, p-Methylphenylurea, p-Tolylcarbamide

4-Methylphenylurea

p-Tolylurea is an apolar molecule that has been shown to have a radiation-protective effect against malignant cells. It can be used as a substitute for pyridine and other nucleophilic reagents in synthesizing condensation products. The mechanism of action of p-tolylurea is still unclear, but it may be due to its ability to inhibit the activity of histone deacetylase enzymes, which are involved in the regulation of cell proliferation and differentiation. This chemical also inhibits serine/threonine protein kinases, which may account for its anticancer activity.

CAS 622-51-5: N-(4-Methylphenyl)urea

4-Methylphenylurea

Ref: 10-F018865

p-Tolylurea

Ref: 3D-FT61354

1-(P-Tolyl)Urea

Ref: 54-OR1008986

p-Tolylurea

Ref: 3B-T0328