CAS 622-64-0: Phenol, 4-[2-(dimethylamino)ethyl]-, sulfate (2:1) (salt)

Hordenine sulfate is a naturally occurring alkaloid, which is derived primarily from plants like barley (Hordeum vulgare) and certain cacti. It is commonly associated with the chemical ecology of these plants, serving as a deterrent against herbivore consumption. The mode of action of hordenine sulfate involves its function as a sympathomimetic agent, primarily through the inhibition of monoamine oxidase (MAO) and the subsequent increase of catecholamines such as norepinephrine. This results in enhanced adrenergic signaling and stimulation of the central nervous system. In scientific research, hordenine sulfate is studied for its pharmacological properties, including potential applications in the modulation of energy metabolism, cognitive function, and mood. Its role in metabolic studies often involves the investigation of its effects on lipid metabolism and weight management, while neurophysiological research explores its impact on neurotransmitter release and receptor sensitivity. Due to its stimulant qualities, hordenine sulfate is also examined for its potential uses in enhancing athletic performance and endurance, although these applications remain under significant scrutiny within the regulatory and scientific communities.