CAS 6233-83-6: Oxytocin Acetate

Oxytocin for NMR identification CRS

OXYTOCIN CRS

Oxytocin acetate

Oxytocin acetate (α-Hypophamine acetate) is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Oxytocin acetate is an analog of oxytocin, which is a hormone that stimulates the uterus during labor. Oxytocin acetate is synthesized by the chemical conjugation of oxytocin with an acetic acid moiety. The stability of this molecule has been shown to be higher than that of oxytocin. This drug has been shown to have stronger binding affinity for the oxytocin receptor, which may be due to its increased molecular weight. Oxytocin acetate has also been shown to increase levels of growth factors and fatty acids in tissues when administered intramuscularly, as well as stimulating neurotransmission. The onset latency for this drug is shorter than that of oxytocin and it produces a longer duration of action in comparison to other analogs. Oxytocin acetate can also be used cosmetically as a disinfectant and can act as an amide-forming agent in organic synthesis reactions.

Applications Oxytocin Acetate is the principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland. References Pierce, et al.: J. Biol. Chem., 199, 929 (1952), Tuppy, et al.: Biochem. Biophys. Acta, 11, 449 (1953), Cash, et al.: J. Med. Pharm. Chem., 5, 413 (1962), Nachtmann, F., et al.: Anal. Profiles Drug Subs., 10, 563 (1981),