CAS 624-38-4: 1,4-Diiodobenzene

1,4-Diiodobenzene is an anti-retroviral drug that is used in the treatment of HIV infection. It has a molecular weight of 208.2 and a melting point of -68°C. 1,4-Diiodobenzene binds to intracellular targets, such as reverse transcriptase, proteases and integrase in HIV-1. This drug also has immunomodulatory effects on T cells and B cells. 1,4-Diiodobenzene has been shown to be effective against bacterial vaginosis and may have beneficial effects on body mass index and fatty acid metabolism.

Applications 1,4-Diidobenzene is used in single molecular bridging of Au nanogaps. It can also form copolymers with ethynylbenzenes in sponge to give elastic hydrophobic materials. References Komoto, Yuki., et al.: J. Phys. Chem. C, 117(46), 24277-24282 (2013)

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1,4-Diiodobenzene is used in Suzuki reaction. It is used as a precursor in the preparation of martinellic acid and 1,4-bis(p-R-phenylethynyl)benzenes. Further, it is employed in the preparation of 1,4-diiodo-2,5-didodecylbenzene , which is a starting reagent for the synthesis of oligo(1,4-phenylene ethynylene). It is also used in human and animal nutrition products including antiseptics and disinfectants. In addition to this, it used in polarizing films for liquid crystal display chemicals. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1,4-Diiodobenzene