CAS 62640-06-6: methyl {(1R,4aR,5S,6R,8aS)-8-hydroxy-5,6-dimethyl-5-[2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl]octahydro-8aH-spiro[naphthalene-1,2'-oxiran]-8a-yl}acetate

Ajugarin II is a naturally occurring iridoid glycoside found in plants belonging to the genus Ajuga, which is a member of the Lamiaceae family. These plants have been traditionally used in herbal medicine and are known for their various pharmacological properties. The source of Ajugarin II is primarily the leaf and stem tissues, where it is biosynthesized as part of the plant's secondary metabolites. The mode of action of Ajugarin II involves the modulation of inflammatory pathways. It is known to inhibit the activity of key enzymes such as cyclooxygenase (COX) and lipoxygenase, which play a critical role in the inflammation process. Additionally, Ajugarin II can scavenge free radicals, contributing to its antioxidant properties, which further support its role in anti-inflammatory activities. Ajugarin II's applications have been explored in the context of its potential therapeutic benefits as an anti-inflammatory agent. It has been the subject of research for its possible uses in treating inflammatory and autoimmune diseases. Experiments have been conducted to investigate its efficacy in reducing symptoms and markers of inflammation in various model systems, which could contribute to the development of targeted therapies in the future.