CAS 6271-81-4: 5-Methoxy-1-naphthalenamine
Formula:C11H11NO
InChI:InChI=1S/C11H11NO/c1-13-11-7-3-4-8-9(11)5-2-6-10(8)12/h2-7H,12H2,1H3
InChI key:InChIKey=UTVXWNASWNYGPB-UHFFFAOYSA-N
SMILES:O(C)C=1C2=C(C(N)=CC=C2)C=CC1
Synonyms:- 5-Methoxy-1-naphthalenamine
- 1-Naphthylamine, 5-methoxy-
- 5-Methoxy-1-naphthylamine
- 1-Amino-5-methoxynaphthalene
- 1-Naphthalenamine, 5-methoxy-
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Found 3 products.
5-Methoxynaphthalen-1-amine
CAS:5-Methoxynaphthalen-1-amine is a ligand for the P-gp efflux pump. It has been shown to have high affinity for this protein, with a Kd of 0.4 nM. This drug also has an optical rotation of [α]D=−5.5° and can be used as a diagnostic ligand in positron emission tomography (PET) imaging studies. 5-Methoxynaphthalen-1-amine can be used to identify binding sites for the P-gp efflux pump, which is often expressed at low levels on tumor cells and is important in promoting resistance to chemotherapeutic drugs. 5-Methoxynaphthalen-1-amine is also a chiral compound that can bind to the receptor subtype P2X7, potentially providing new insights into how these receptors contribute to inflammation and pain pathways.Formula:C11H11NOPurity:Min. 95%Molecular weight:173.21 g/mol
