Trans-glutaconic acid is an organic compound characterized by its structure as a dicarboxylic acid, specifically an unsaturated derivative of glutamic acid. It features a trans configuration around its double bond, which distinguishes it from its cis counterpart. The molecular formula of trans-glutaconic acid is C5H6O4, and it contains two carboxylic acid functional groups (-COOH) that contribute to its acidic properties. This compound is typically found in a crystalline form and is soluble in water, which enhances its reactivity in various chemical processes. Trans-glutaconic acid is of interest in biochemical research, particularly in studies related to amino acid metabolism and potential applications in pharmaceuticals. Its structural characteristics allow it to participate in various chemical reactions, including esterification and decarboxylation. Additionally, it may serve as an intermediate in the synthesis of other organic compounds. Overall, trans-glutaconic acid is a significant compound in organic chemistry with implications in both biological systems and synthetic applications.

trans-Glutaconic acid

628-48-8: 2-Pentenedioic acid, (E)-, 2-Pentenedioic acid, (2E)-, Glutaconic acid, (E)-, (2E)-2-Pentenedioic acid, Glutaconic acid, trans-

Applications trans-Glutaconic Acid is used in the synthesis of iso and azokainoids which act as agonists for glutamate receptors. E-isomer of Glutaconic Acid (G596945).
References Felluga, F. et al.: Chirality, 24, 112 (2012); Wang, W. et al.: Bioorg. Med. Chem. Lett., 23, 1949 (2013);


trans-Glutaconic Acid

(E)-Pent-2-enedioic acid

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CAS 628-48-8: trans-Glutaconic acid

trans-Glutaconic Acid

Ref: TR-G596940

trans-Glutaconic acid

Ref: 54-OR20037

(E)-Pent-2-enedioic acid

Ref: IN-DA003QRP

(E)-2-Pentenedioic acid

Ref: 3D-FP45766