CAS 628-71-7: 1-Heptyne

1-Heptyne is a small molecule that can be produced from fatty acids. It has been shown to be an effective homogeneous catalyst for the palladium-catalyzed coupling of unsaturated fatty acids and formaldehyde. 1-Heptyne is also a component of medicinal preparation, activated with chloride and hydrogen bond donor, which are used to treat autoimmune diseases. The frequency shift in the infrared spectrum of 1-heptyne has been shown to be related to the presence of nitrogen atoms in its structure.

1-Heptyne is used in the synthesis of (6Z,10E,12Z)-octadeca-6,10,12-trienoic acid and (8Z,12E,14Z)-eicosa-8,12,14-trienoic acid. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications 1-Heptyne can be used for cycloisomerization of alkynyl imines and alkynylation of oxiranes. References Kel’in, A. V., et al.: J. Am. Chem. Soc. 123, 2074 (2001); Yamaguichi, M., et al.: Tetrahedron Lett. 24, 391 (1983)

Hept-1-yne