CAS 632-22-4: Tetramethylurea

Tetramethylurea is used as a solvent in dyestuff industries, in condensation reaction and intermediates in surfactant. It is utilized for base catalyzed isomerization and alkylation hydrocyanation due to its low permittivity. It reacts with oxalyl chloride to prepare tetramethyl chloroformamidinium chloride, which is used for the conversion of carboxylic acids and dialkyl phosphates to anhydrides and pyrophosphates respectively. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Tetramethylurea is an excellent solvent for organic substances, in particular aromatic compounds. References Lüttringhaus, A., et al.: Angew. Chem. Int. Ed. Engl., 3, 260 (1964)

Tetramethylurea is a versatile compound that has various applications in different fields. It is commonly used as a monophosphate donor in biochemical reactions and as a reagent for the synthesis of L-sorbose and histidine. In addition, tetramethylurea is employed in the production of herbicides, as well as in the synthesis of zirconium oxide nanoparticles. Furthermore, tetramethylurea plays a crucial role in scientific research as it acts as an NK-1 receptor antagonist and an arginase inhibitor. These properties make it valuable for studying neurological disorders and metabolic pathways. Moreover, tetramethylurea can be used as a selectable marker in genetic engineering experiments due to its ability to neutralize the toxic effects of certain compounds such as benzoate. This feature allows researchers to easily identify cells that have successfully incorporated specific plasmids. Overall, tetramethylurea is an essential compound with diverse applications across various industries and scientific disciplines. Its unique properties

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1,1,3,3-Tetramethylurea