CAS 6320-02-1: 2-Bromothiophenol

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Bromothiophenol

2-Bromo-benzenethiol is a bifunctional reagent that can be used to synthesize amines by the amination of aldehydes and ketones. This reaction is selective for primary and secondary alcohols, with tertiary alcohols being unreactive. The substrate molecule is typically an amine or hydrazine. The most common reaction mechanism involves nucleophilic attack at the carbonyl carbon followed by protonation of the resulting enolate. 2-Bromobenzene thiol has been shown to react with fatty acids in a reductive amination reaction. It also has a trifluoromethyl group, which gives it properties that are hydrophilic.