CAS 63208-82-2: Pifithrin
Formula:C16H18N2OS·BrH
InChI:InChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H
InChI key:InChIKey=HAGVCKULCLQGRF-UHFFFAOYSA-N
SMILES:C(C(=O)C1=CC=C(C)C=C1)N2C3=C(SC2=N)CCCC3.Br
Synonyms:- Pifithrin
- Ethanone, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-, hydrobromide (1:1)
- Pifithrin-α
- Ethanone, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-, monohydrobromide
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Found 8 products.
Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurity:100% - 98.54%Color and Shape:SolidMolecular weight:367.32-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3-yl)-1-(4-methylphenyl)ethanone,hydrobromide
CAS:Formula:C16H19BrN2OSPurity:98%Color and Shape:SolidMolecular weight:367.3039Pifithrin-α
CAS:Formula:C16H18N2OS·HBrPurity:>98.0%(T)(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:367.31Pifithrin-α
CAS:Formula:C16H18N2OS·HBrPurity:≥ 98%Color and Shape:White to off-white powderMolecular weight:367.301-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
CAS:1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide is a pro-apoptotic molecule that induces apoptosis in various cancer cell lines. It has been shown to induce apoptosis by activating pro-apoptotic protein Bax and mitochondrial membrane potential (Δψm) loss. 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide also inhibits angiogenesis by blocking the activation of basic proteins and the angiogenic process. In vitro studies have demonstrated that this compound binds to response elements on DNA that are associated with tumor suppression genes and causes neuronal death.Purity:Min. 95%
