Acetamide, 2-(4-nitrophenoxy)-, also known by its CAS number 63218-14-4, is an organic compound characterized by the presence of an acetamide functional group and a 4-nitrophenoxy substituent. This compound typically appears as a solid or crystalline substance and is soluble in polar solvents due to its amide functionality. The presence of the nitro group introduces significant polarity and can influence the compound's reactivity and interaction with other molecules. Acetamides are generally known for their stability and can participate in various chemical reactions, including nucleophilic substitutions and acylation processes. The 4-nitrophenoxy group may impart specific biological activities or enhance the compound's properties for applications in pharmaceuticals or agrochemicals. Additionally, the compound's melting point, boiling point, and other physical properties can vary based on purity and environmental conditions. As with many organic compounds, safety precautions should be taken when handling this substance, as it may pose health risks if ingested or inhaled.

Acetamide, 2-(4-nitrophenoxy)-

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2-(4-nitrophenoxy)acetamide

2-(4-Nitrophenoxy)acetamide is a cytotoxic agent that was originally synthesized for cancer treatment. It is a potent inhibitor of topoisomerases I and II, which are enzymes essential to DNA replication. The crystal structure of 2-(4-Nitrophenoxy)acetamide has been determined. This compound exhibits significant cytotoxicity in cancer cell lines and potentiates the efficacy of other agents in cancer therapy. 2-(4-Nitrophenoxy)acetamide also inhibits connective tissue cells, which can lead to tumor regression.

CAS 63218-14-4: Acetamide, 2-(4-nitrophenoxy)-

2-(4-nitrophenoxy)acetamide

Ref: IN-DA00JGYV

2-(4-Nitrophenoxy)acetamide

Ref: 3D-FN131704

2-(4-Nitrophenoxy)acetamide

Ref: 10-F350233