CAS 63231-63-0: RNA

Ribonucleic acid CRS

Ribonucleic acid (RNA) from baker?s yeast S. cerevisiae may be used as a substrate for studying ribonuclease activities of enzymes such as RNAase(s). It is also suitable for use as a carrier in nucleic acid purification and precipitation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Ribonucleic acid free acid (ribo-FAA) is a derivative of the immunosuppressive drug rapamycin. It is an immunosuppressant that inhibits the immune system by binding to a protein called FKBP12, which is involved in the activation of T cells and other immune system cells. Ribo-FAA has been shown to be effective in treating HIV patients undergoing active antiretroviral therapy, as well as for treatment of other infectious diseases such as tuberculosis or leishmaniasis. Ribo-FAA binds to FKBP12 and prevents it from activating T cells or other immune system cells, which leads to suppression of the immune response.