CAS 63422-71-9: (αR)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic acid

(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenylacetic acid is a useful organic compound for research related to life sciences. The catalog number is T65534 and the CAS number is 63422-71-9.

Applications (R)-α-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic acid is used in the preparation of cephem derivatives, as antibacterial agents. References Albrecht, H.A., et al.: J. Med. Chem., 34, 2857 (1991);

(R)-(-)-a-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic Acid is an inhibitor of the enzyme histamine N-methyltransferase (HNMT), which is responsible for the synthesis of histamine. The inhibition of HNMT leads to a decrease in histamine levels and therefore has been used as a treatment for chronic prostatitis, lacrimal gland, and energy efficiency. Histamine N-methyltransferase also participates in the regulation of apoptosis by methylating proapoptotic proteins like Bax, so inhibition can lead to an increase in apoptosis. This chemical is also able to bind with chloride ions and form diphenyl ethers through a reaction solution, which are known to have anticancer properties.

(R)-(-)-α-[[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)Carbonyl]Amino]Benzeneacetic Acid

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi