
CAS 63659-18-7: Betaxolol
Formula:C18H29NO3
InChI:InChI=1S/C18H29NO3/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3
InChI key:InChIKey=NWIUTZDMDHAVTP-UHFFFAOYSA-N
SMILES:O(CC(CNC(C)C)O)C1=CC=C(CCOCC2CC2)C=C1
Synonyms:- 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-
- 1-Isopropylamino-3-[4-(2-cyclopropylmethoxy-ethyl)phenoxy]-2-propanol
- Betaxolol
- Betoptic S
- 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol
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Found 7 products.
Betaxolol
CAS:Controlled ProductBetaxolol is a cardioselective beta-adrenergic blocker that has been shown to reduce intraocular pressure in patients with primary open-angle glaucoma. It is also used for the treatment of cardiac arrhythmias and high blood pressure. Betaxolol is an ester prodrug that is hydrolyzed by esterases to its active form, betaxolol hydrochloride (BXH). Betaxolol hydrochloride has a significant cytotoxic effect on cells through inhibition of DNA synthesis. A majority of BXH is eliminated from the body unchanged via renal excretion, however some BXH is metabolized by cytochrome P450 enzymes to inactive metabolites. The pharmacokinetics of this drug can be monitored by measuring plasma concentrations of betaxolol and betaxolol hydrochloride. Betaxolol may be determined by analytical methods such as x-ray diffraction data and electrochemical impedanceFormula:C18H29NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:307.43 g/molBetaxolol Hydrochloride
CAS:Formula:C18H29NO3·HClPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:343.89Betaxolol
CAS:Applications Cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma. References Cadigan, P.J., et al.: Br. J. Clin. Pharmacol., 9, 569 (1980), Pathe, M., et al.: Therapie, 37, 75 (1982),Formula:C18H29NO3Color and Shape:Off-WhiteMolecular weight:307.43Betaxolol
CAS:Betaxolol (Kerlone) is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.Formula:C18H29NO3Purity:99.01%Color and Shape:White Crystalline SolidMolecular weight:307.43