CAS 63722-91-8: (3R,5bS,7aS,13bS,13cR,15aS)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-Dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-4H-3,15a-epoxy-1-benzoxepino[6′,7′:6,7]indeno[1,2-b]indol-4-one

Paspalinine is a mycotoxin, which is a naturally occurring toxic compound. It is produced by certain fungi, specifically within the genera of Aspergillus and Penicillium, which often proliferate in damp or improperly stored agricultural products. The mode of action of paspalinine involves interference with cellular biochemical pathways, potentially disrupting normal cellular functions due to its interaction with specific cellular receptors or enzymes. Paspalinine's uses and applications primarily reside in the field of scientific research. Due to its potent biological activity, it serves as a model compound in studies exploring fungal toxicity, biosynthesis of mycotoxins, and their effects on various biological systems. While not applied directly in industrial or pharmaceutical products, understanding the pathways and mechanisms related to paspalinine contributes to advancing the fields of toxicology, microbiology, and mycology, and aids in developing strategies to mitigate mycotoxin contamination in food supplies. Further research into its structural and functional dynamics continues to provide insights into its role in fungal ecology and its potential impact on health.

Paspalinine blocks ChTX binding to bovine maxi-K channels and inhibits GABAA, causing tremors.