CAS 63824-12-4: 1-[(2Z)-2-(4-Chlorophenyl)-3-(2,4-dichlorophenyl)-2-propen-1-yl]-1H-imidazole

Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.

Aliconazole is a triazole-based antifungal agent, which is a synthetic derivative developed through chemical synthesis. It functions by inhibiting the enzyme lanosterol 14α-demethylase, crucial in the biosynthesis of ergosterol, a vital component of fungal cell membranes. By disrupting ergosterol production, aliconazole compromises the structural integrity of the cell membrane, leading to increased permeability and eventual cell death. Aliconazole is utilized primarily in the treatment of fungal infections due to its broad-spectrum efficacy against various pathogenic fungi, including both yeasts and molds. Its ability to target the enzymatic pathways specific to fungal cells while sparing mammalian mechanisms makes it a valuable tool in both clinical and agricultural settings. The compound's stability and effectiveness in inhibiting fungal growth are key attributes that continue to be explored in different formulations and delivery systems. Research into its potential applications ensures that aliconazole remains a significant focus in the development of antifungal therapies.