CAS 63902-38-5: Pinoresinol diglucoside

Pinoresinol diglucopyranoside is a natural compound found in Chinese herb. It has been shown to have an anti-atherosclerotic effect, which may be due to the inhibition of nuclear factor kappa-light-chain-enhancer (NF-κB) and matrix metalloproteinase (MMP)-9. Pinoresinol diglucopyranoside also inhibits collagenase activity in vitro and reduces inflammation in vivo. The molecular mechanism of this compound may involve the toll-like receptor 4 (TLR4) pathway, which is responsible for immune responses to bacterial products. Pinoresinol diglucopyranoside has been shown to inhibit the transcription and polymerization of DNA by binding to DNA gyrase and topoisomerase IV, respectively.

Pinoresinol diglucoside

Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) is a putative α-glucosidase inhibiting compound ,and a important antihypertensive compound.

Pinoresinol diglucopyranoside is a lignan glycoside, which is a type of polyphenolic compound. It is predominantly sourced from various plant species, including flaxseeds, sesame seeds, and olives. This compound is distinguished by its intricate glycosidic linkages, which play a crucial role in its biological activity. As an antioxidant, pinoresinol diglucopyranoside functions by neutralizing free radicals, thus reducing oxidative stress in cells. Its mode of action involves modulating biochemical pathways and interacting with specific cellular receptors to exert protective effects against cellular damage. In research settings, pinoresinol diglucopyranoside has attracted attention for its potential applications in nutraceuticals and pharmaceuticals. It is studied for its cardiovascular benefits, potential anti-cancer properties, and role in regulating lipid metabolism. Its ability to modulate inflammatory responses further underscores its significance in developing therapeutic agents aimed at chronic conditions. Given its biological activities, pinoresinol diglucopyranoside continues to be a subject of interest for scientists exploring natural compounds with health-promoting qualities.

Pinoresinol diglucoside is a putative α-glucosidase inhibiting compound, has antihypertensive activity. It is a heat shock factor 1 inducer, increased expression of HSF1 by a factor of 1.041 at 3 μM.

Pinoresinol Diglucoside

Natural glycoside

Stability Hygroscopic Applications Pinoresinol Diglucoside is a sugar lignan which inhibits α-glucosidase in vitro, displaying the ability to act as a hypoglycemic agent. References Owen, R. et al.: Eur. J. Canc., 10, 1235 (2000);