CAS 63911-32-0: Benzoic acid,4-hydroxy-3-methoxy-, (3-endo)-8-azabicyclo[3.2.1]oct-3-yl ester

Convolidin is a vinca alkaloid, which is a type of indole alkaloid renowned for its pharmacological properties. This compound is derived from plants in the Convulvulaceae family, specifically from the bindweed species. Vinca alkaloids are biosynthesized from the tryptophan and iridoid pathways, exhibiting a complex molecular architecture typical of plant-derived alkaloids. The mode of action of Convolidin primarily involves the disruption of microtubule function. It binds to tubulin, thereby inhibiting microtubule assembly, which results in the arrest of mitotic cell division. This mechanism is well-documented in literature as a key feature of vinca alkaloids, contributing to their utility in disrupting cellular proliferation. Convolidin is studied for its potential applications in oncological research. Due to its ability to interfere with cell division, it has been explored in the development of chemotherapeutic agents, particularly targeting rapidly dividing cancer cells. Its therapeutic potential makes it a subject of interest for scientists investigating innovative cancer treatments and the pharmacodynamics of plant-derived alkaloids.

Natural alkaloid