CAS 64431-96-5: Bis-tris propane

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

BIS-TRIS propane (BTP), a novel multidentate ligand of nickel- and cobalt-based spin clusters, is a metal chelator.

1,3-Bis[tris(hydroxymethyl)methylamino]propane is used as a buffer for polymerase chain reaction and molecular biology. It is also used with hydrochloric acid buffer for stabilization of farnesyl diphosphate isolated from a strain of saccharomyces cerevisiae. It acts as a ligand and forms dinuclear hydroxo complexes with Lanthanides(III). Further, it is useful for calibration of genetically encoded pH indicators expressed in the cytosol or mitochondria. It is also employed to investigate the influence of anions with varying nucleophilic properties on the autoxidation of oxymyoglobin. In addition to this, it is used in the purification of glucose-binding protein from membranes of sulfolobus solfataricus and as a non-zwitterionic buffer, which is used in the pH range between 6.3 and 9.5. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

BIS-TRIS propane

1,3-Bis[tris(hydroxymethyl)methylamino]propane is a compound that has been shown to inhibit the growth of prostate cancer cells in tissue culture. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is used to extract and purify DNA from biological samples. It binds to DNA by electrostatic interactions with the phosphate groups on the nucleotide backbone, which induces cell lysis. This molecule has also been shown to be an inhibitor of polymerase chain reaction (PCR), a technique used for amplifying target sequences in DNA. The redox potential of this molecule can be measured using cyclic voltammetry. The compound also reacts with monoclonal antibodies specific for prostate cancer cells and inhibits their binding to prostate cancer cells. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is a reactive compound that contains a

BIS-TRIS propane

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.