Oxprenolol is a non-selective beta-adrenergic antagonist, commonly used in the treatment of hypertension and certain cardiac conditions. It functions by blocking the action of catecholamines like adrenaline on beta-adrenergic receptors, leading to a decrease in heart rate and blood pressure. Chemically, it is characterized by its structure, which includes a phenolic hydroxyl group and a propanolamine moiety, contributing to its pharmacological activity. Oxprenolol exhibits moderate lipophilicity, allowing it to cross biological membranes effectively. It is typically administered orally and has a relatively short half-life, necessitating multiple doses throughout the day for sustained therapeutic effects. The substance may also exhibit some intrinsic sympathomimetic activity, which can lead to a less pronounced reduction in heart rate compared to other beta-blockers. As with many medications, potential side effects include fatigue, dizziness, and gastrointestinal disturbances, and it should be used with caution in patients with respiratory conditions due to its non-selective nature. Overall, Oxprenolol represents an important option in the management of cardiovascular diseases.

Oxprenolol

6452-71-7: (.+-.)-Oxprenolol, 1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol, 1-(Isopropylamino)-2-hydroxy-3-[o-(allyloxy)phenoxy]propane, 1-(Propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol, 1-[(1-Methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-2-propanol, 1-[o-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol, 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-, 2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-, Coretal, dl-Oxprenolol, 1-(2-allyloxyphenoxy)-3-isopropylaminopropan-2-ol, 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-

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Applications Oxprenolol is a free base of Oxprenolol Hydrochloride(O870500) which is a β-Adrenergic blocker. Antihypertensive, antianginal, antiarrhythmic.
References Garteiz, et al.: J. Pharmacol. Exp. Ther., 179, 354 (1971), Taylor, S.H., et al.: N. Engl. J. Med., 307, 1293 (1982),


CAS 6452-71-7: Oxprenolol

Oxprenolol

Ref: 3D-GAA45271

Oxprenolol

Ref: TR-O871500

Oxprenolol

Ref: 4Z-O-151