CAS 6453-67-4: pyropheophorbide A methyl ester
Formula:C34H36N4O3
InChI:InChI=1/C34H36N4O3/c1-8-20-16(3)24-13-26-18(5)22(10-11-31(40)41-7)33(37-26)23-12-30(39)32-19(6)27(38-34(23)32)15-29-21(9-2)17(4)25(36-29)14-28(20)35-24/h8,13-15,18,22,35-36H,1,9-12H2,2-7H3/b24-13-,25-14-,26-13-,27-15-,28-14-,29-15-,33-23-
SMILES:C=Cc1c(C)c2=CC3=NC(=C4CC(=O)C5=C(C)C(=Cc6c(CC)c(C)c(C=c1[nH]2)[nH]6)N=C45)C(CCC(=O)OC)C3C
Synonyms:- 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, methyl ester, (3S,4S)-
- Pyrophaeophorbide-a-monomethyl ester
- Methyl 4-(9-Ethenyl-14-Ethyl-4,8,13-Trimethyl-20-Oxophorbin-3-Yl)Butanoate
- Methyl 3-(9-Ethenyl-14-Ethyl-4,8,13,18-Tetramethyl-20-Oxo-24,25-Dihydrophorbin-3-Yl)Propanoate
- Methyl pyropheophorbide-a
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Found 6 products.
Pyropheophorbide A Methyl Ester
CAS:Controlled ProductStability Light Sensitive Applications Pyropheophorbide A Methyl Ester is a chlorophyll (C379815) analog for studies of photosynthesis. Methyl pyropheophorbide a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, and is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide a has photodynamic activity and can induce apoptosis and inhibit tumor growth. References Bensasson, R., et al.: Nature, 290, 329 (1981); Moore, A., et al.: Science, 216, 982 (1982)Formula:C34H36N4O3Color and Shape:NeatMolecular weight:548.67Methyl pyropheophorbide-a
CAS:MPPa, a PDT photosensitizer derived from chlorophyll a, absorbs at 667/674 nm with no dark cytotoxicity.Formula:C34H36N4O3Purity:98.17%Color and Shape:SolidMolecular weight:548.67Pyropheophorbide a methyl ester
CAS:Pyropheophorbide a methyl ester is an organic compound that is used in photodynamic therapy. It binds to hemoglobin, which is the oxygen-carrying protein of red blood cells. The binding of pyropheophorbide a methyl ester to hemoglobin causes it to become unstable and break down into reactive molecules that are cytotoxic. The carbonyl group on this molecule also makes it a good substrate for ABCG2, which is a transporter protein found on the surface of cancer cells. This drug has shown success in treating prostate cancer cells and herpes simplex virus. Pyropheophorbide a methyl ester has been shown to produce tumour necrosis when irradiated with UVB light, by inducing apoptosis and inducing the production of reactive oxygen species.Formula:C34H36N4O3Purity:Min. 95%Molecular weight:548.67 g/mol
