Guanosine 5'-(beta,gamma-imido)triphosphate lithium salt, commonly referred to as GMP-PNP, is a nucleotide analog that plays a significant role in biochemical research, particularly in studies involving G-proteins and nucleotide-binding proteins. This compound mimics the structure of guanosine triphosphate (GTP) but features a modified phosphate group, which makes it resistant to hydrolysis. As a result, GMP-PNP is often used to stabilize the active form of G-proteins in vitro, allowing researchers to investigate their function and interactions without the complications of rapid GTP turnover. The lithium salt form enhances its solubility in aqueous solutions, making it suitable for various experimental applications. GMP-PNP is typically a white to off-white powder, and it is soluble in water, which facilitates its use in biological assays. Its stability and ability to act as a non-hydrolyzable GTP analog make it a valuable tool in molecular biology and biochemistry for studying signal transduction pathways and enzyme mechanisms.

guanosine 5'-(beta,gamma-imido)triphos phate li4-salt

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Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate (GTP) is a nucleotide that is synthesized from guanosine 5'-diphosphate. GTP is an effector molecule that regulates the cytosolic protein synthesis and transport pathways. It binds to a number of proteins, including the guanine nucleotide-binding protein, which regulates the metabolic processes in cells. GTP has been shown to be beneficial in treating cancer by inducing apoptosis and inhibiting tumor growth. In addition, Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate has been shown to inhibit congestive heart failure by reducing free radical production and increasing intracellular adenosine levels.

Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate

Guanosine 5''-[β,γ-imido]triphosphate tetralithium salt hydrate

GUANYLYL-5'-IMIDODIPHOSPHATE, TETRALITHIUM SALT

Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.

CAS 64564-03-0: guanosine 5'-(beta,gamma-imido)triphos phate li4-salt

Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate

Ref: 3D-PCA56403

Guanosine 5''-[β,γ-imido]triphosphate tetralithium salt hydrate

Ref: 7W-GK2200

GUANYLYL-5'-IMIDODIPHOSPHATE, TETRALITHIUM SALT

Ref: IN-DA00E8UY

Guanylyl Imidodiphosphate (lithium salt)

Ref: TM-T36009