CAS: 648927-86-0

Firibastat

(3R)-3-Amino-4-[[(2R)-2-amino-4-sulfobutyl]disulfanyl]butane-1-sulfonic acid is a peptide that has been shown to activate the ATPase activity of the receptor. This peptide binds to the extracellular domain of the receptor and inhibits its interaction with ligands and other proteins. The CAS number for this compound is 648927-86-0. (3R)-3-Amino-4-[(2R)-2-(aminosulfonyl)butyldisulfanyl]butane 1 sulfonic acid is soluble in water, methanol, and DMSO.

Firibastat (RB150) is a glutamyl aminopeptidase antagonist and an orally active brain penetrating prodrug of EC33.