Benzene, 1-iodo-4-(methylsulfonyl)-, also known as 4-Iodo-methylsulfonylbenzene, is an organic compound characterized by a benzene ring substituted with an iodine atom and a methylsulfonyl group at the para position. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is known for its aromatic properties, which contribute to its stability and reactivity. The presence of the iodine atom makes it a potential electrophile in various chemical reactions, while the methylsulfonyl group can enhance its solubility in polar solvents and influence its reactivity. Benzene derivatives like this compound are often used in organic synthesis, pharmaceuticals, and agrochemicals. Safety considerations include handling it in a well-ventilated area and using appropriate personal protective equipment, as it may pose health risks if inhaled or ingested. Overall, its unique structure and functional groups make it a valuable compound in synthetic organic chemistry.

Benzene, 1-iodo-4-(methylsulfonyl)-

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1-Iodo-4-(methylsulfonyl)benzene

1-Iodo-4-(methylsulfonyl)benzene is a positron emission probe that can be used for the measurement of cyclooxygenase-2 (COX-2) activity. It is synthesized by reacting 1-iodobenzene with methylsulfonyl chloride in the presence of triethylamine. The positron emitted during this reaction is detected by a high resolution gamma camera, which allows the detection and quantification of COX-2 activity. This probe has been shown to be an effective inhibitor of COX-2 activity, and its use may provide an alternative method for monitoring COX-2 activity in vivo.

CAS 64984-08-3: Benzene, 1-iodo-4-(methylsulfonyl)-

1-Iodo-4-(methylsulfonyl)benzene

Ref: 54-OR470154

1-Iodo-4-(methylsulfonyl)benzene

Ref: IN-DA00F7IE

1-Iodo-4-(methylsulfonyl)benzene

Ref: 10-F790710

1-Iodo-4-(methylsulfonyl)benzene

Ref: 3D-PCA98408