6-[(4-Nitrobenzyl)sulfanyl]-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine, with CAS number 65199-10-2, is a purine derivative characterized by the presence of a ribofuranosyl moiety and a phosphono group, which contribute to its biological activity. The compound features a sulfanyl group linked to a 4-nitrobenzyl substituent, enhancing its potential for interactions in biochemical pathways. This structure suggests that it may exhibit properties relevant to nucleoside analogs, potentially influencing nucleic acid metabolism or serving as a substrate for various enzymes. The nitro group may also impart unique electronic properties, affecting the compound's reactivity and interaction with biological targets. Additionally, the presence of the phosphono group indicates potential for involvement in phosphorylation processes, which are critical in cellular signaling and energy transfer. Overall, this compound's unique structural features position it as a candidate for further investigation in medicinal chemistry and biochemistry, particularly in the context of antiviral or anticancer research.

6-[(4-nitrobenzyl)sulfanyl]-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine

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Applications Used in therapy of mouse leukemia L1210 in combinations with Nebularin and Nitrobenzylthioinosine 5’-monophosphate.
References Anderson, C., et al.: Neurosci. Lett., 219, 191 (1996), Allay, J., et al.: Nat. Med., 4, 1136 (1998),


6-[(4-Nitrobenzyl)thio]-9-Beta-D-ribofuranosylpurine-5’-monophosphate, Disodium Salt

6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is a modified nucleoside that has anticancer activity. It is phosphorylated to the corresponding nucleotide in vivo and inhibits the growth of cancer cells. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt has a novel structure and can be used as an activator for ribonucleotides or deoxyribonucleotides. It is also used as a component in DNA synthesis, which may be due to its ability to inhibit viral RNA replication. This drug can be synthesized through chemical reactions that involve diphosphate, nucleosides, and phosphoramidites. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is not currently available on the market; however, it can

CAS 65199-10-2: 6-[(4-nitrobenzyl)sulfanyl]-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine

6-[(4-Nitrobenzyl)thio]-9-Beta-D-ribofuranosylpurine-5’-monophosphate, Disodium Salt

Ref: TR-N495770

6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt

Ref: 3D-NN07313