Toluidine blue, also known as toluidine blue O, is a synthetic dye belonging to the thiazine class of compounds. It is characterized by its deep blue color and is commonly used as a biological stain in histology and cytology due to its ability to bind to nucleic acids and certain proteins. The dye exhibits metachromasia, meaning it can change color when bound to different types of tissues, which enhances its utility in microscopy. Toluidine blue is soluble in water and alcohol, making it versatile for various applications. In addition to its staining properties, it has been employed in medical diagnostics, particularly in identifying certain types of tumors and in the detection of mast cells. The compound has a relatively low toxicity profile, but safety precautions should still be observed during handling. Its chemical structure includes an amino group, contributing to its basicity and interaction with biological molecules. Overall, toluidine blue is a valuable tool in both research and clinical settings for visualizing cellular components.

toluidine blue

6586-04-5: N-(7-amino-8-methyl-3H-phenothiazin-3-ylidene)-N-methylmethanaminium chloride

Toluidine blue is a drug that inhibits the growth of bacteria. It has antimicrobial activity against oral pathogens and is used in the diagnosis of bowel disease, such as Crohn's disease. Toluidine blue has been used to treat squamous carcinoma with a high degree of success. This compound also inhibits the development of cancer cells by interfering with cell division and blocking DNA synthesis. Toluidine blue binds to the bacterial membrane, which prevents it from taking up nutrients and leads to cell death.

CAS 6586-04-5: toluidine blue

Toluidine blue

Ref: 3D-FT171697

TOLUIDINE BLUE FOR MICROSCOPY

Ref: IN-DA00FCO1