CAS 65899-73-2: Tioconazole
Formula:C16H13Cl3N2OS
InChI:InChI=1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2
InChI key:InChIKey=QXHHHPZILQDDPS-UHFFFAOYSA-N
SMILES:C(CN1C=CN=C1)(OCC2=C(Cl)SC=C2)C3=C(Cl)C=C(Cl)C=C3
Synonyms:- 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl) ethyl]-1H-imidazole
- 1-[2-[(2-Chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)-ethyl]imidazole
- 1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
- 1H-Imidazole, 1-[2-[(2-chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-
- Fungibacid
- Gyno-Trosyd
- New Straitus U
- Tioconazol
- Trosyd
- Trosyl
- Vagistat
- See more synonyms
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Found 16 products.
Tioconazole for system suitability CRS
CAS:Tioconazole for system suitability CRSFormula:C16H13Cl3N2OSColor and Shape:Crystalline Powder. White. Powder.Molecular weight:387.71121-[(2S)-2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
CAS:Formula:C16H13Cl3N2OSPurity:98%Color and Shape:SolidMolecular weight:387.7112Tioconazole, Ph. Eur. grade
CAS:Formula:C16H13Cl3N2OSPurity:≤ 0.1%Color and Shape:White to almost white powderMolecular weight:387.71Tioconazole
CAS:Controlled ProductApplications Tioconazole is an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical). References Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),Formula:C16H13Cl3N2OSColor and Shape:WhiteMolecular weight:387.71Tioconazole
CAS:Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols.Formula:C16H13Cl3N2OSPurity:99.57%Color and Shape:SolidMolecular weight:387.71Tioconazole
CAS:TioconazoleFormula:C16H13Cl3N2OSPurity:99.6%Color and Shape:WhiteMolecular weight:385.98142Tioconazole
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C16H13Cl3N2OSColor and Shape:PowderMolecular weight:385.98142Tioconazole
CAS:Formula:C16H13Cl3N2OSPurity:≥ 98.0% (dried basis)Color and Shape:White or almost white powder or crystalsMolecular weight:387.71Tioconazole
CAS:Tioconazole is an antifungal agent, which is a synthetic derivative of imidazole with broad-spectrum activity against fungi. This compound is chemically synthesized through complex organic reactions to enhance its antimycotic efficacy. Tioconazole functions by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane. By disrupting the ergosterol biosynthesis pathway, tioconazole destabilizes the fungal cell membrane, leading to increased permeability and eventual cell death. Tioconazole is primarily utilized in the treatment of superficial fungal infections such as vulvovaginal candidiasis. It is applied topically, often in the form of creams or ointments, directly to the affected area. Its mode of action ensures that the antifungal effects are localized, thereby minimizing systemic absorption and associated side effects. Due to its potent activity and broad-spectrum efficacy, tioconazole serves as a critical option in clinical settings where resistance to other antifungal agents may be present. The precise targeting of ergosterol synthesis underscores its role as a vital component in contemporary antifungal therapy.Formula:C16H13Cl3N2OSPurity:Min. 95%Molecular weight:387.71 g/mol
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